homeImaging in 2020
September 18 - 22, 2011
Final Program
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Sunday, September 18
4:00 - 6:00pm Registration and Poster Setup
6:00 - 7:00pm Dinner
7:00 - 7:15pm Welcome
7:15 - 9:00pm Imaging biological processes
- Chair Remarks, Dan Sullivan
- Jan Schnitzer (Proteogenomics Research Institute)
"Proteomic imaging to penetrate key biological barriers in vivo"
- Tom Meade, Northwestern U.,
"How far have we come on the road to 2020?"
9:00 - 10:00pm Reception and Poster Session
Monday, September 19
7:00 - 8:00am Breakfast
8:00 - 9:45am Session II - Epigenetics
- Chair Remarks, Tom Aigner
- Jacob Hooker (MGH) "Visualization of Chromatin-modifying
Enzymes with Positron Emission Tomography"
- Harold Craighead (Cornell) "Approaches for single molecule
epigenetic analysis
Groundbreaking discoveries about the brain have revolutionized our understanding of addiction, enabling us to respond effectively to the problem. This session is focused on new imaging methods to interrogate brain function and disease.
9:45 - 10:15am Group Photo, Break
10:15 - 12:00pm Session III - Imaging in nanotechnology
- Chair Remarks, Belinda Seto
- Kit Lam (UC Davis) "Versatile Nanoplatform for Cancer
Imaging and Therapy"
- Jinming Gao - (UT Southwestern Medical Center, Dallas)
"pH-Activatable ON/OFF Nanosystems for Cancer Imaging and
Therapeutic Delivery"
Novel chemistries for theragnostics, including micelles can overcome imaging and delivery barriers. Here, the applications of these techniques in the delivery of siRNA and chemotherapeutics will be summarized along with future applications.
12:00 - 1:00pm Lunch
1:00 - 5:00pm Afternoon free time
6:00 - 6:45pm Reception
6:45 - 7:45pm Dinner
7:45 - 7:55pm Introduction of Keynote Speaker
7:55 - 8:55pm Keynote Address, Don Listwin, Canary Foundation
"Molecular Imaging in Early Cancer Detection"Tuesday, September 20
7:00 - 8:00am Breakfast
8:00 - 9:45am Session IV - Imaging and cellular therapy
- Chair Remarks, Tom Meade
- Gang Bao (Georgia Tech/Emory) "Fluorescent and Nanoparticle
Imaging Probes for Biological and Disease Studies"
- Joseph Wu, MD (Stanford) "Pluripotent Stem Cell Therapy:
Insights from Molecular Imaging"
Novel imaging techniques on both the sub-cellular and cellular scale provide key information to optimize cellular machines and regenerative therapies.
9:45 - 10:00am Break
10:00-11:45pm Session V - New targets and their application in therapeutics
and monitoring
- Chair Remarks, Dean Sherry
- John Frangioni, (Beth Israel Deaconess Medical Center, Boston)
"Image-Guided Surgery using Near-Infrared Light"
- Martin Pomper, MD (Johns Hopkins) "Theranostics for Oncology"
New targeting approaches have been developed based on one-bead, one -compound chemistries and structure-activity relationship studies. These new targeting ligands have been applied to enhance delivery and monitoring of therapies.
11:45 - 12:45pm Lunch
12:45 - 6:00pm Afternoon free time
6:00 - 7:15pm Dinner
7:15 - 9:00pm Session VI - Imaging and siRNA
- Chair Remarks, Angelique Louie
- John Rossi (City of Hope) "RNA interference (RNAi):
Challenges and Opportunities"
- "Niren Murthy (Georgia Tech) "New strategies for treating and
imaging oxidative stress and infectious diseases"
While RNA interference shows great promise in the treatment of a wide spectrum of disease states, the delivery of such therapeutics has been problematic. Here, the state of the art in the clinical and pre-clinical applications of RNA therapies will be reviewed and the role of imaging described.
9:00 - 10:00pm Reception and Poster Session
Wednesday, September 21
7:00 - 8:00am Breakfast
8:00 - 9:45am Session VII - Industry
- Chair Remarks, Katherine Ferrara
- Wolfgang Ruhm (Bruker Bio-Spin) "Preclinical MRI - Paving
the Way to 2020"
- Daniel Bradley (Millennium) "Imaging Cancer Biomarkers"
- Jeff Peterson (Perkin-Elmer) "Quantitative Whole Body
Biodistribution of Fluorescent-Labeled Agents by
Non-Invasive Tomographic Imaging"
- Adrian Nunn (Bracco) "How to identify and quantify specific
targeted bubble binding in clinical ultrasound molecular
imaging: lessons from preclinical imaging"
9:45 - 10:00am Break
10:00 - 11:45am Session VII - Imaging in nanotechnology II
- Chair Remarks, Kit Lam
- Greg Lanza (Wash U, St Louis) "Novel sn-2 Lipase Labile
Prodrugs Optimize Drug Delivery with Targeted
Lipid-based Nanoparticles"
- Gang Zheng (U Toronto) "Porphysomes: Intrinsically theranostic
organic nanophotonics"
This session will focus on the latest nanoparticle designs for multimodal imaging and delivery of PDT agents, drugs and siRNAs.
11:45 - 12:30pm Lunch
12:45 - 6:00pm Afternoon free time
6:00 - 7:00pm Dinner
7:00 - 8:45pm Session VIII - Imaging and activatable particles
- Chair Remarks, Keyvan Farahani
- Matt Dreher (NIH) "Image-guided drug delivery"
- Sanders Langereis (Philips) "MR Imaging of drug release from
temperature-sensitive liposomes"
Imaging techniques to follow both the pharmacokinetics of particles and the release of their cargo facilitate image-guided drug delivery and its application in interventional radiology. Both transcatheter arterial chemoembolization (TACE) and MR-guided focused ultrasound benefit from new strategies to image nanoparticles.
8:45 - 10:00pm Reception and Poster Session
Thursday, September 22
7:00 - 8:00am Breakfast
8:00 - 9:30am Session IX - Imaging and new contrast mechanisms
- Simon Cherry (UC Davis) "Imaging Faster than the Speed of Light
with Cerenkov Radiation"
- Simon Duckett (University of York, UK) "Transfer of parahydrogen
orders of magnitude"
The lectures will describe the latest in clinical applications of optical imaging and some of the newest technologies for creating hyperpolarized materials for biological imaging.
9:30 - 9:45am Break
9:45 - 11:15am Session X - Optical imaging and mass spectrometry
- Hulya Bayir (Univ. Pittsburgh) "Mass spectrometric imaging of
oxidized lipids"
- Clemens Lowik (Leiden Univ.) "Dual Colour Whole Body Optical
Imaging and Other new Tools: Translation Into The Clinic"
11:15 - 11:30pm Concluding Remarks